October 2025 Newsletter: At Pharmalys, Quality is More Than a Goal – It’s our Promise

Patients’ Treatment Expectations Influence Health Outcomes

Why Patients’ Expectations Matter

Patients’ expectations in the context of medical treatment represent a growing area of research, with increasing evidence suggesting their impact on health outcomes across a wide range of physical and mental health conditions. For example, expectations have been associated with treatment course and outcomes in patients with heart disease, stroke, cancer, musculoskeletal disorders, injuries, and obesity. They have also been shown to predict outcomes in patients undergoing various types of surgery. Moreover, expectations are a key mechanism underlying the placebo and nocebo effects – a phenomena in which subjective and physiological changes occur due to inert or non-specific treatment components.

Positive expectations may lead to improved treatment outcomes, whereas negative expectations can result in reduced efficacy and an increase in adverse effects. Effectively managing patient expectations may therefore improve treatment success and reduce the need for additional interventions arising from dissatisfaction or side effects following the initial consultation.

Difficulties in Synthesising Current Evidence 

Despite a growing number of studies examining expectations across different medical conditions, integrating existing findings remains challenging. A major limitation identified in several systematic reviews and meta-analyses is the heterogeneity in how expectations are conceptualised and assessed. Read more

AI and the Future of Women’s Health

 

 

 

When we talk about artificial intelligence (AI) revolutionising healthcare, the conversation often centres on speed, efficiency, and innovation. But too often, it misses a crucial point: technology alone won’t fix the systemic inequalities already embedded in medicine. Without deliberate action, AI risks amplifying the very biases that have historically sidelined women’s health.

Women’s Health: A Concerning Context 

Women’s health has long been an afterthought in medical research and practice. The result? Conditions that disproportionately or uniquely affect women (like endometriosis or polycystic ovary syndrome) remain underexplored, underdiagnosed, and undertreated. On average, it takes seven years for a woman in France to receive an endometriosis diagnosis, a delay that compounds suffering and limits treatment options.

In its report Taking into account sex and gender to better treat: a public health issue (2020), the High Council for Equality between Women and Men warns about the impact of gender stereotypes in medical practice: persistent biases that can wrongly guide a diagnosis, delay it, or even prevent it, affecting both women and men.

Take the example of cardiovascular disease. It remains perceived as a “male” pathology in the collective imagination, typically associated with the image of a stressed, middle-aged man with a cigarette in hand. Thus, with identical symptoms, a woman complaining of chest tightness is three times more likely to be prescribed anxiolytics than a man, for whom the same clinical picture will more often trigger a referral to a cardiologist.

These inequalities do not only affect women. On the contrary, certain conditions are still perceived as “feminine”, such as depression or osteoporosis, and are consequently less often diagnosed in men. Read more.

 

At Pharmalys, Quality is More Than a Goal – It’s our Promise

At Pharmalys, quality is at the heart of everything we do. From leadership decisions to daily operations, we embed excellence, consistency, and accountability into every service we deliver. Our approach ensures reliable results, regulatory compliance, and the trust of our partners worldwide.

What Quality Means to Us

Consistency

Clear standards, dependable services

Accountability

We own results, track performance, and act quickly on issues

Innovation

Data, feedback, and technology fuel our evolution

Risk Mitigation

Reducing errors and non-compliance safeguards timelines and outcomes

Compliance

Full alignment with ICH GCP, GCLP, and local regulatory requirements

What This Means for You

Reliable Results. Fewer errors, consistently high standards
Greater Efficiency. Best practices streamline timelines and outcomes
Built-in Trust. Transparent, proactive problem-solving
Access to Expertise. Clear Deep GxP knowledge, extensive industry experience
True Partnership. A joint commitment to excellence and success

Contracted Services:

  • Investigator Site Audit
  • Vendor Audits: Phase I centre, vendor, and GCLP audits
  • Project Audits: TMF, safety project, and database audits
  • Document Audits: Protocols, Clinical Study Reports
  • Inspection Support: Inspection readiness, regulatory inspection preparation visit on-site, site and sponsor inspection support
  • Additional Services: GCP/GCLP training, SOP development, GxP consulting

Contact Us Today to learn more about our Quality services

 

GOOD CLINICAL LABORATORY PRACTICE (GCLP) ACCREDITATION SCHEME

Operated by Pharmalys Ltd

The GCLP Accreditation Scheme is specifically designed for laboratories around the world that analyse samples from clinical trials. It aims to:

  • Enhance Quality: Ensure that laboratories adhere to rigorous standards, producing accurate, complete, and consistent data/results
  • Promote Compliance: Align laboratory practices with international regulatory requirements and guidelines
  • Mitigate Risks: Reduce risk of error and non-compliance, which can lead to costly delays or failures in clinical trials
  • Foster Trust: Build confidence among stakeholders, including sponsors, regulatory bodies and patients and in the quality of laboratory data

The scheme has been managed globally by Tim Stiles, CEO of Qualogy 2002 Ltd, since 2003. Pharmalys took over full management of the scheme in 2025.

Benefits of Joining the Scheme

  • Gain Recognition: Achieve a mark of excellence that distinguishes your laboratory in the competitive field of clinical research
  • Improve Efficiency: Implement best practices that streamline operations and enhance productivity
  • Access Expertise: Benefit from our extensive experience and support in maintaining high standards of laboratory practice
  • Boost Credibility: Enhance your laboratory’s reputation and trust-worthiness with accredited status

For more information about the GCLP accreditation scheme, visit our website.

Contact Us Today for more information