Patients’ Treatment Expectations Influence Health Outcomes
Why Patients’ Expectations Matter
Patients’ expectations in the context of medical treatment represent a growing area of research, with increasing evidence suggesting their impact on health outcomes across a wide range of physical and mental health conditions. For example, expectations have been associated with treatment course and outcomes in patients with heart disease, stroke, cancer, musculoskeletal disorders, injuries, and obesity. They have also been shown to predict outcomes in patients undergoing various types of surgery. Moreover, expectations are a key mechanism underlying the placebo and nocebo effects – a phenomena in which subjective and physiological changes occur due to inert or non-specific treatment components.
Positive expectations may lead to improved treatment outcomes, whereas negative expectations can result in reduced efficacy and an increase in adverse effects. Effectively managing patient expectations may therefore improve treatment success and reduce the need for additional interventions arising from dissatisfaction or side effects following the initial consultation.
Difficulties in Synthesising Current Evidence
Despite a growing number of studies examining expectations across different medical conditions, integrating existing findings remains challenging. A major limitation identified in several systematic reviews and meta-analyses is the heterogeneity in how expectations are conceptualised and assessed. Read more.
AI and the Future of Women’s Health
When we talk about artificial intelligence (AI) revolutionising healthcare, the conversation often centres on speed, efficiency, and innovation. But too often, it misses a crucial point: technology alone won’t fix the systemic inequalities already embedded in medicine. Without deliberate action, AI risks amplifying the very biases that have historically sidelined women’s health.
Women’s Health: A Concerning Context
Women’s health has long been an afterthought in medical research and practice. The result? Conditions that disproportionately or uniquely affect women (like endometriosis or polycystic ovary syndrome) remain underexplored, underdiagnosed, and undertreated. On average, it takes seven years for a woman in France to receive an endometriosis diagnosis, a delay that compounds suffering and limits treatment options.
In its report Taking into account sex and gender to better treat: a public health issue (2020), the High Council for Equality between Women and Men warns about the impact of gender stereotypes in medical practice: persistent biases that can wrongly guide a diagnosis, delay it, or even prevent it, affecting both women and men.
Take the example of cardiovascular disease. It remains perceived as a “male” pathology in the collective imagination, typically associated with the image of a stressed, middle-aged man with a cigarette in hand. Thus, with identical symptoms, a woman complaining of chest tightness is three times more likely to be prescribed anxiolytics than a man, for whom the same clinical picture will more often trigger a referral to a cardiologist.
These inequalities do not only affect women. On the contrary, certain conditions are still perceived as “feminine”, such as depression or osteoporosis, and are consequently less often diagnosed in men. Read more.
At Pharmalys, Quality is More Than a Goal – It’s our Promise
What Quality Means to Us
Consistency
Clear standards, dependable services
Accountability
We own results, track performance, and act quickly on issues
Innovation
Data, feedback, and technology fuel our evolution
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Reducing errors and non-compliance safeguards timelines and outcomes
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What This Means for You
Contracted Services:
- Investigator Site Audit
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- Project Audits: TMF, safety project, and database audits
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GOOD CLINICAL LABORATORY PRACTICE (GCLP) ACCREDITATION SCHEME
Operated by Pharmalys Ltd
The GCLP Accreditation Scheme is specifically designed for laboratories around the world that analyse samples from clinical trials. It aims to:
- Enhance Quality: Ensure that laboratories adhere to rigorous standards, producing accurate, complete, and consistent data/results
- Promote Compliance: Align laboratory practices with international regulatory requirements and guidelines
- Mitigate Risks: Reduce risk of error and non-compliance, which can lead to costly delays or failures in clinical trials
- Foster Trust: Build confidence among stakeholders, including sponsors, regulatory bodies and patients and in the quality of laboratory data
The scheme has been managed globally by Tim Stiles, CEO of Qualogy 2002 Ltd, since 2003. Pharmalys took over full management of the scheme in 2025.
Benefits of Joining the Scheme
- Gain Recognition: Achieve a mark of excellence that distinguishes your laboratory in the competitive field of clinical research
- Improve Efficiency: Implement best practices that streamline operations and enhance productivity
- Access Expertise: Benefit from our extensive experience and support in maintaining high standards of laboratory practice
- Boost Credibility: Enhance your laboratory’s reputation and trust-worthiness with accredited status
For more information about the GCLP accreditation scheme, visit our website.

